The incident happened in the Creeslough area
Emergency services are responding to reports of an explosion in the Creeslough area of Co Donegal.
The explosion is understood to have happened at a filling station.
Independent Councillor John O'Donnell said there was a "massive explosion" with damage to a shop and an apartment complex.
In a statement, gardaí said they are "assisting other emergency services at the scene of a serious incident".
Gardaí are asking any road users intending to travel to Creeslough to consider alternative routes.
According to Donegal Daily, a number of cars have been damaged as a result of falling debris.
The main part of the building which also contains apartments have been severely damaged.