The drugs originated in the Netherlands.
Ecstasy and Ketamine worth an estimated 108-thousand euro have been seized at a premises in Athlone.
The drugs originated in the Netherlands and were destined for addresses in Dublin and Waterford.
They were discovered in parcels on Tuesday.
Separately, Revenue officers examining parcels at a premises in Dublin last week seized drugs and prescription medicines with an estimated value of 206-thousand euro.
They originated in the USA, Canada, Spain, India and the UK and were destined for addresses nationwide.
Two imitation firearms were also seized and investigations are ongoing.