Leo Varadkar says misinformation must also be tackled.
The Taoiseach has admitted the government needs to communicate better with the public about immigration.
The admission comes after a suspected arson attack on a hotel, due to house 70 asylum seekers, in Galway.
Gardaí have launched a criminal investigation after the former Ross Lake House in Rosscahill, went up in flames on Saturday night.
It's not the first time a building earmarked for asylum seekers has been damaged by fire.
The Government Chief Whip, Hildegarde Naughton, say there needs to be more consultation with communities where asylum seekers are due to be accommodated.
Leo Varadkar added that misinformation must also be tackled:
"We've a job to do as a government to communicate with people better on migration.
"I'm concerned about the level of misinformation, quite frankly, that is out there.
"We've a duty, as does the media by the way, in making sure that we're all informed."
Following the incident, Justice Minister Helen McEntee says those responsible for the fire should be held accountable.
She accepts there's limited accommodation, but insists the government has been engaging with local communities.
Minister McEntee admits similar attacks could happen again, but Gardaí will do everything to protect people:
"Every effort is being made to protect people, not just those in accomodation, but to protect people right across the country.
"The Gardaí respond in the way they are trained to do so, and I fully support the work that they do.
"Any type of crime like this, it has a strong penalty, and people need to be held accountable."