The cuts will come into effect over the next few years.
Bank of Ireland is to cut 1,400 jobs in the coming years.
The bank says it has launched a voluntary redundancy programme across the group this morning.
It says in the medium term, it expects to reduce its staff numbers from 10,400 to less than 9,000.
The bank lost €669 million before tax in the first half of this year. That's after putting aside €937 million, mainly to cover losses related to Covid-19.
Bank of Ireland CEO Francesca McDonagh told RTÉ News that:
"We're being prudent and comprehensive in taking that large provision. Everything has to be seen through the prism of Covid-19"
"Two thirds relate to expected credit losses, one third is actual credit losses. We're being quite clear to the market today that we would see the majority of the full year impairment charge - between 70 and 85% of the full year - being taken in the first six months."